Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis

Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis

We explore cell heterogeneity during spontaneous and transcription-factor-driven commitment for network inference in hematopoiesis. Since individual genes display discrete OFF states or a distribution of ON levels, we compute and combine pairwise gene associations from binary and continuous componen...

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Bibliographic Details
Main Authors: Cristina Pina, José Teles, Cristina Fugazza, Gillian May, Dapeng Wang, Yanping Guo, Shamit Soneji, John Brown, Patrik Edén, Mattias Ohlsson, Carsten Peterson, Tariq Enver
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005288

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http://www.sciencedirect.com/science/article/pii/S2211124715005288

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