Luminal localization of α-tubulin K40 acetylation by cryo-EM analysis of fab-labeled microtubules.

The αβ-tubulin subunits of microtubules can undergo a variety of evolutionarily-conserved post-translational modifications (PTMs) that provide functional specialization to subsets of cellular microtubules. Acetylation of α-tubulin residue Lysine-40 (K40) has been correlated with increased microtubul...

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Bibliographic Details
Main Authors: Virupakshi Soppina, Jeffrey F Herbstman, Georgios Skiniotis, Kristen J Verhey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3482196?pdf=render