The Gamma-Butyrolactone Model of Absence Epilepsy: Acute and Chronic Effects in Wistar Rats

The Gamma-Butyrolactone Model of Absence Epilepsy: Acute and Chronic Effects in Wistar Rats

Objectives: We studied the electroencephalographic (EEG) and behavioral changes of the chemical model of generalized absence epilepsy induced by acute and chronic administration of gamma-butrolactone (GBL), a prodrug of gamma-hydroxybutyric acid.Methods: Adult male Wistar rats under anesthesia were...

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Bibliographic Details
Main Authors: Tuğba ERYİĞİT KARAMAHMUTOĞLU, Nihan ÇARÇAK, Melike ŞAHİNER, Özlem AKMAN, O. Carter SNEAD, Esat EŞKAZAN, Filiz ONAT
Format: Article
Language:English
Published: KARE Publishing 2013-01-01
Series:Epilepsi
Subjects:
Absence epilepsy
gamma-butyrolactone
wistar rats
EEG.
Online Access:http://www.journalagent.com/z4/download_fulltext.asp?pdir=epilepsi&plng=tur&un=JTES-65365

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http://www.journalagent.com/z4/download_fulltext.asp?pdir=epilepsi&plng=tur&un=JTES-65365

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