Caloric Restriction and Diet-Induced Weight Loss Do Not Induce Browning of Human Subcutaneous White Adipose Tissue in Women and Men with Obesity

Caloric Restriction and Diet-Induced Weight Loss Do Not Induce Browning of Human Subcutaneous White Adipose Tissue in Women and Men with Obesity

Caloric restriction (CR) is standard lifestyle therapy in obesity management. CR-induced weight loss improves the metabolic profile of individuals with obesity. In mice, occurrence of beige fat cells in white fat depots favors a metabolically healthy phenotype, and CR promotes browning of white adip...

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Bibliographic Details
Main Authors: Valentin Barquissau, Benjamin Léger, Diane Beuzelin, Frédéric Martins, Ez-Zoubir Amri, Didier F. Pisani, Wim H.M. Saris, Arne Astrup, Jean-José Maoret, Jason Iacovoni, Sébastien Déjean, Cédric Moro, Nathalie Viguerie, Dominique Langin
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Subjects:
human obesity
caloric restriction
dietary intervention
subcutaneous abdominal white adipose tissue
browning of white fat
uncoupling protein 1
sex difference
insulin resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471731954X

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http://www.sciencedirect.com/science/article/pii/S221112471731954X

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