Analgesic Effect of Zanthoxylum nitidum Extract in Inflammatory Pain Models Through Targeting of ERK and NF-κB Signaling

Analgesic Effect of Zanthoxylum nitidum Extract in Inflammatory Pain Models Through Targeting of ERK and NF-κB Signaling

BackgroundZanthoxylum nitidum (Roxb.) DC., also named Liang Mianzhen (LMZ), one kind of Chinese herb characterized with anti-inflammatory and relieving pain potency, which is widely used to treat injuries, rheumatism, arthralgia, stomach pain and so on in China. But its mechanism related to the anti...

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Bibliographic Details
Main Authors: Fenfen Qin, Han Zhang, Anlong Liu, Qisheng Wang, Qinmei Sun, Shengfeng Lu, Qian Li, Hongwei Guo, Xing Liu, Zhigang Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
Zanthoxylum nitidum
Liang Mianzhen
inflammatory pain
pro-inflammatory cytokines
NF-κBp65
p-ERK1/2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00359/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00359/full

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