Astrocyte-specific regulation of hMeCP2 expression in Drosophila

Alterations in the expression of Methyl-CpG-binding protein 2 (MeCP2) either by mutations or gene duplication leads to a wide spectrum of neurodevelopmental disorders including Rett Syndrome and MeCP2 duplication disorder. Common features of Rett Syndrome (RTT), MeCP2 duplication disorder, and neuro...

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Bibliographic Details
Main Authors: David L. Hess-Homeier, Chia-Yu Fan, Tarun Gupta, Ann-Shyn Chiang, Sarah J. Certel
Format: Article
Language:English
Published: The Company of Biologists 2014-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/3/11/1011