miR-15b induced by platelet-derived growth factor signaling is required for vascular smooth muscle cell proliferation

The platelet-derived growth factor (PDGF) signaling pathway isessential for inducing a dedifferentiated state of vascular smoothmuscle cells (VSMCs). Activation of PDGF inhibits smoothmuscle cell (SMC)-specific gene expression and increases the rateof proliferation and migration, leading to dediffer...

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Bibliographic Details
Main Authors: Hara Kang, Sunghwan Kim
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-11-01
Series:BMB Reports
Subjects:
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMTI3MThAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xMSU1RDEzMTEyNzE4MjZfJTI4NTUwLTU1NCUyOUJNQl8xMy0wNTcucGRm