Pore formation by human stefin B in its native and oligomeric states and the consequent amyloid induced toxicity.

It is well documented that amyloid forming peptides and proteins interact with membranes and that this correlates with cytotoxicity. To introduce the theme we give a brief description of some amyloidogenic proteins and note their similarities with pore forming toxins and cell penetrating peptides. H...

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Bibliographic Details
Main Authors: Gregor eAnderluh, Eva eZerovnik
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00085/full