MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis

MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis

Abstract Background Endometrial carcinoma (EC) is one of the most common malignancies of the female reproductive system. Migration and invasion inhibitory protein (MIIP) gene was recently discovered candidate tumor suppress gene which located at chromosome 1p36.22. 1p36 deletion was found in many ty...

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Bibliographic Details
Main Authors: Yingmei Wang, Limei Hu, Ping Ji, Fei Teng, Wenyan Tian, Yuexin Liu, David Cogdell, Jinsong Liu, Anil K. Sood, Russell Broaddus, Fengxia Xue, Wei Zhang
Format: Article
Language:English
Published: BMC 2016-10-01
Series:Journal of Hematology & Oncology
Subjects:
Endometrial cancer
MIIP
Migration
Rac1/PAK1 pathway
Tumor suppressor gene
Online Access:http://link.springer.com/article/10.1186/s13045-016-0342-6

Internet

http://link.springer.com/article/10.1186/s13045-016-0342-6

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