The Dynamic Partnership of Polycomb and Trithorax in Brain Development and Diseases

Epigenetic mechanisms, including DNA and histone modifications, are pivotal for normal brain development and functions by modulating spatial and temporal gene expression. Dysregulation of the epigenetic machinery can serve as a causal role in numerous brain disorders. Proper mammalian brain developm...

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Bibliographic Details
Main Authors: Janise N. Kuehner, Bing Yao
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/3/3/17