Memory decline in Down syndrome and its relationship to iPF2alpha, a urinary marker of oxidative stress.

Lipid peroxidation may be a marker of free-radical-mediated injury associated with Alzheimer's disease (AD). We aimed to investigate whether changes in lipid peroxidation is associated with cognitive decline in individuals with Down syndrome over a 4-year period.Thirty-two adults with DS partic...

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Bibliographic Details
Main Authors: Panagiotis Zis, Patrick McHugh, Andrew McQuillin, Domenico Praticò, Mark Dickinson, Sima Shende, Zuzana Walker, Andre Strydom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4046955?pdf=render