The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?

The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?

Abstract Background Silica continues to represent an intriguing topic of fundamental and applied research across various scientific fields, from geology to physics, chemistry, cell biology, and particle toxicology. The pathogenic activity of silica is variable, depending on the physico-chemical feat...

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Bibliographic Details
Main Authors: Cristina Pavan, Massimo Delle Piane, Maria Gullo, Francesca Filippi, Bice Fubini, Peter Hoet, Claire J. Horwell, François Huaux, Dominique Lison, Cristina Lo Giudice, Gianmario Martra, Eliseo Montfort, Roel Schins, Marialore Sulpizi, Karsten Wegner, Michelle Wyart-Remy, Christina Ziemann, Francesco Turci
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Particle and Fibre Toxicology
Subjects:
Silica
Silicosis
Lung cancer
Auto-immune diseases
Surface reactivity
Silanol
Online Access:http://link.springer.com/article/10.1186/s12989-019-0315-3

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http://link.springer.com/article/10.1186/s12989-019-0315-3

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