Dexamethasone enhances the efficacy of atorvastatin in inhibiting excessively inflammation-induced abnormal angiogenesis by regulating macrophages

Dexamethasone enhances the efficacy of atorvastatin in inhibiting excessively inflammation-induced abnormal angiogenesis by regulating macrophages

Abstract Background We have recently showed that atorvastatin (ATO) combined with low dose of dexamethasone (DEX) was more efficacious in treating patients with chronic subdural haematoma (CSDH) than ATO monotherapy. This study was designed to investigate the underlying mechanisms of the improved ef...

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Bibliographic Details
Main Authors: Zhitao Gong, Daqiang Zhan, Meng Nie, Xiaochun Li, Chuang Gao, Xuanhui Liu, Tangtang Xiang, Jiangyuan Yuan, Weiwei Jiang, Jinhao Huang, Wei Quan, Dong Wang, Ye Tian, Hengjie Yuan, Jianning Zhang, Rongcai Jiang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Neuroinflammation
Subjects:
Chronic subdural haematoma
Atorvastatin
Dexamethasone
Macrophages
Inflammation
Angiogenesis
Online Access:https://doi.org/10.1186/s12974-021-02257-1

Internet

https://doi.org/10.1186/s12974-021-02257-1

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