A New Method for Ethical and Efficient Evidence Generation for Off-Label Medication Use in Oncology (A Case Study in Glioblastoma)

A New Method for Ethical and Efficient Evidence Generation for Off-Label Medication Use in Oncology (A Case Study in Glioblastoma)

In oncology, preclinical and early clinical data increasingly support the use of a number of candidate “non-cancer” drugs in an off-label setting against multiple tumor types. In particular, metabolically targeted drugs show promise as adjuvant chemo and radiosensitizers, improving or restoring sens...

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Bibliographic Details
Main Authors: Samir Agrawal, Padman Vamadevan, Ndaba Mazibuko, Robin Bannister, Raphael Swery, Shanna Wilson, Sarah Edwards
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
off-label
glioblastoma
metformin
atorvastatin
mebendazole
doxycycline
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00681/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00681/full

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