The subfamily-specific interaction between Kv2.1 and Kv6.4 subunits is determined by interactions between the N- and C-termini.

The subfamily-specific interaction between Kv2.1 and Kv6.4 subunits is determined by interactions between the N- and C-termini.

The "silent" voltage-gated potassium (KvS) channel subunit Kv6.4 does not form electrically functional homotetramers at the plasma membrane but assembles with Kv2.1 subunits, generating functional Kv2.1/Kv6.4 heterotetramers. The N-terminal T1 domain determines the subfamily-specific assem...

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Bibliographic Details
Main Authors: Elke Bocksteins, Evy Mayeur, Abbi Van Tilborg, Glenn Regnier, Jean-Pierre Timmermans, Dirk J Snyders
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24901643/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24901643/?tool=EBI

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