PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3β/β-catenin/cyclin D1 signaling pathway in ER-negative breast cancer

Abstract Background A growing amount of evidence has indicated that PSAT1 is an oncogene that plays an important role in cancer progression and metastasis. In this study, we explored the expression and function of PSAT1 in estrogen receptor (ER)-negative breast cancer. Method The expression level of...

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Bibliographic Details
Main Authors: Song Gao, Anqi Ge, Shouping Xu, Zilong You, Shipeng Ning, Yashuang Zhao, Da Pang
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-017-0648-4