Trophoblast lineage specification in the mammalian preimplantation embryo

Abstract Background The establishment of the trophectoderm (TE) and the inner cell mass (ICM) is the first cell lineage segregation that occurs in mammalian preimplantation development. TE will contribute to the placenta while ICM cells give rise to the epiblast (EPI) and primitive endoderm (PrE). T...

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Bibliographic Details
Main Author: Yayoi Toyooka
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Reproductive Medicine and Biology
Subjects:
Online Access:https://doi.org/10.1002/rmb2.12333