Multiple myeloma hinders erythropoiesis and causes anaemia owing to high levels of CCL3 in the bone marrow microenvironment

Multiple myeloma hinders erythropoiesis and causes anaemia owing to high levels of CCL3 in the bone marrow microenvironment

Abstract Anaemia is the most common complication of myeloma and is associated with worse clinical outcomes. Although marrow replacement with myeloma cells is widely considered a mechanistic rationale for anaemia, the exact process has not been fully understood. Our large cohort of 1363 myeloma patie...

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Bibliographic Details
Main Authors: Lanting Liu, Zhen Yu, Hui Cheng, Xuehan Mao, Weiwei Sui, Shuhui Deng, Xiaojing Wei, Junqiang Lv, Chenxing Du, Jie Xu, Wenyang Huang, Shuang Xia, Gang An, Wen Zhou, Xiaoke Ma, Tao Cheng, Lugui Qiu, Mu Hao
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77450-y

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https://doi.org/10.1038/s41598-020-77450-y

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