Novel Solid Dispersions of Naphthoquinone Using Different Polymers for Improvement of Antichagasic Activity

Novel Solid Dispersions of Naphthoquinone Using Different Polymers for Improvement of Antichagasic Activity

IVS320 (3a,10b-dihydro-1<i>H</i>-cyclopenta[<i>b</i>]naphtho[2,3-<i>d</i>]furan-5,10-dione) is a naphthoquinone that has low solubility in aqueous medium, a physical behavior that limits its biological activities, considering that compounds from this class have se...

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Bibliographic Details
Main Authors: Verônica da Silva Oliveira, Elen Diana Dantas, Anna Thereza de Sousa Queiroz, Johny Wysllas de Freitas Oliveira, Marcelo de Sousa da Silva, Patricia Garcia Ferreira, Fernando de Carvalho da Siva, Vitor Francisco Ferreira, Ádley Antonini Neves de Lima
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceutics
Subjects:
solid dispersion
delivery system
polymeric carriers
antichagasic activity
Online Access:https://www.mdpi.com/1999-4923/12/12/1136

Internet

https://www.mdpi.com/1999-4923/12/12/1136

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