Polarized secretion of interleukin (IL)-6 and IL-8 by human airway epithelia 16HBE14o- cells in response to cationic polypeptide challenge.

BACKGROUND: The airway epithelium participates in asthmatic inflammation in many ways. Target cells of the epithelium can respond to a variety of inflammatory mediators and cytokines. Damage to the surface epithelium occurs following the secretion of eosinophil-derived, highly toxic cationic protein...

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Bibliographic Details
Main Authors: Alison Wai-ming Chow, Jocelyn Feng-ting Liang, Janice Siu-chong Wong, Yan Fu, Nelson Leung-sang Tang, Wing-hung Ko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2920803?pdf=render