Redox Dependent Modifications of Ryanodine Receptor: Basic Mechanisms and Implications in Heart Diseases

Heart contraction vitally depends on tightly controlled intracellular Ca regulation. Because contraction is mainly driven by Ca released from the sarcoplasmic reticulum (SR), this organelle plays a particularly important role in Ca regulation. The type two ryanodine receptor (RyR2) is the major SR C...

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Bibliographic Details
Main Authors: Roman Nikolaienko, Elisa Bovo, Aleksey V. Zima
Format: Article
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Physiology
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