Pathophysiology of Myelodysplastic Syndromes

Pathophysiology of Myelodysplastic Syndromes

Ineffective hematopoiesis is the major characteristic of early myelodysplastic syndromes. Its pathophysiology relies on a diversity of mechanisms supported by genetic events that develop in aging hematopoietic stem cells. Deletion and mutations trigger epigenetic modifications, and co-transcriptiona...

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Bibliographic Details
Main Authors: Michaela Fontenay, Batoul Farhat, Ismael Boussaid
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Hemato
Subjects:
ineffective erythropoiesis
mutations
deletions
epigenetics
splicing
translation
Online Access:https://www.mdpi.com/2673-6357/2/3/30

Internet

https://www.mdpi.com/2673-6357/2/3/30

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