Efficiency, selectivity, and robustness of nucleocytoplasmic transport.

All materials enter or exit the cell nucleus through nuclear pore complexes (NPCs), efficient transport devices that combine high selectivity and throughput. NPC-associated proteins containing phenylalanine-glycine repeats (FG nups) have large, flexible, unstructured proteinaceous regions, and line...

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Bibliographic Details
Main Authors: Anton Zilman, Stefano Di Talia, Brian T Chait, Michael P Rout, Marcelo O Magnasco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1914370?pdf=render