Selective toxicity of Caspian cobra (Naja oxiana) venom on liver cancer cell mitochondria

Selective toxicity of Caspian cobra (Naja oxiana) venom on liver cancer cell mitochondria

Objective: To explore the cytotoxicity effects of Caspian cobra (Naja oxiana or N. oxiana) venom on hepatocytes and mitochondria obtained from the liver of HCC rats. Methods: In this study, HCC was induced by diethylnitrosamine (DEN), as an initiator, and 2-acetylaminofluorene (2-AAF), as a promoter...

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Bibliographic Details
Main Authors: Enayatollah Seydi, Shabnam Babaei, Amir Fakhri, Jalal Pourahmad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-05-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Naja oxiana
Apoptosis
Hepatocellular carcinoma
Hepatocytes
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S222116911630750X

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http://www.sciencedirect.com/science/article/pii/S222116911630750X

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