Anti-Inflammatory and Immunomodulatory Effects of the <i>Grifola frondosa</i> Natural Compound <i>o</i>-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κβ and MAPK

Anti-Inflammatory and Immunomodulatory Effects of the <i>Grifola frondosa</i> Natural Compound <i>o</i>-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κβ and MAPK

In response to foreign or endogenous stimuli, both microglia and astrocytes adopt an activated phenotype that promotes the release of pro-inflammatory mediators. This inflammatory mechanism, known as neuroinflammation, is essential in the defense against foreign invasion and in normal tissue repair;...

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Bibliographic Details
Main Authors: Sarah Tomas-Hernandez, Jordi Blanco, Santiago Garcia-Vallvé, Gerard Pujadas, María José Ojeda-Montes, Aleix Gimeno, Lluís Arola, Luisa Minghetti, Raúl Beltrán-Debón, Miquel Mulero
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
microglia
astrocytes
neuro-inflammation
immunomodulation
<i>Grifola frondosa</i>
natural compounds
Online Access:https://www.mdpi.com/1999-4923/13/6/806

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https://www.mdpi.com/1999-4923/13/6/806

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