Local Immune Control of Latent Herpes Simplex Virus Type 1 in Ganglia of Mice and Man

Local Immune Control of Latent Herpes Simplex Virus Type 1 in Ganglia of Mice and Man

Herpes simplex virus type 1 (HSV-1) is a prevalent human pathogen. HSV-1 genomes persist in trigeminal ganglia neuronal nuclei as chromatinized episomes, while epithelial cells are typically killed by lytic infection. Fluctuations in anti-viral responses, broadly defined, may underlay periodic react...

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Bibliographic Details
Main Authors: Anthony J. St. Leger, David M. Koelle, Paul R. Kinchington, Georges Michel G. M. Verjans
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
HSV-1
latency
ganglion
mouse
human
intrinsic immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.723809/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.723809/full

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