Cortical and Subcortical Alterations in Medication Overuse Headache

Medication-overuse headache is an increasing problem in headache clinics and therapy includes drug withdrawal. Although it has been shown that the orbitofrontal cortex is hypo-metabolic and exhibits less gray matter in these patients the functional role of this finding is still unclear as virtually...

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Bibliographic Details
Main Authors: Jan Mehnert, Julia Hebestreit, Arne May
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00499/full