Ibrutinib dose modifications in the management of CLL

Abstract Background Ibrutinib is a Bruton tyrosine kinase inhibitor approved for the treatment of chronic lymphocytic leukemia (CLL) in 2014. Ibrutinib is often used to treat patients who are younger than the patients originally included in theclinical trials have additional unfavorable prognostic f...

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Bibliographic Details
Main Authors: Camille Hardy-Abeloos, Rachel Pinotti, Janice Gabrilove
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Hematology & Oncology
Subjects:
CLL
Online Access:http://link.springer.com/article/10.1186/s13045-020-00870-w