Accurate LC peak boundary detection for ¹⁶O/¹⁸O labeled LC-MS data.

In liquid chromatography-mass spectrometry (LC-MS), parts of LC peaks are often corrupted by their co-eluting peptides, which results in increased quantification variance. In this paper, we propose to apply accurate LC peak boundary detection to remove the corrupted part of LC peaks. Accurate LC pea...

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Bibliographic Details
Main Authors: Jian Cui, Konstantinos Petritis, Tony Tegeler, Brianne Petritis, Xuepo Ma, Yufang Jin, Shou-Jiang S J Gao, Jianqiu Michelle Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792097?pdf=render