Deletion at an 1q24 locus reveals a critical role of long noncoding RNA DNM3OS in skeletal development

Deletion at an 1q24 locus reveals a critical role of long noncoding RNA DNM3OS in skeletal development

Abstract Background Skeletal development and maintenance are complex processes known to be coordinated by multiple genetic and epigenetic signaling pathways. However, the role of long non-coding RNAs (lncRNAs), a class of crucial epigenetic regulatory molecules, has been under explored in skeletal b...

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Bibliographic Details
Main Authors: Ting-ting Yu, Qiu-fan Xu, Si-Yang Li, Hui-jie Huang, Sarah Dugan, Lei Shao, Jennifer A. Roggenbuck, Xiao-tong Liu, Huai-ze Liu, Betsy A. Hirsch, Shen Yue, Chen Liu, Steven Y. Cheng
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Cell & Bioscience
Subjects:
Skeletal abnormalities
1q24
lncRNA
DNM3OS
Nerve growth factor
Online Access:https://doi.org/10.1186/s13578-021-00559-8

Internet

https://doi.org/10.1186/s13578-021-00559-8

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