Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning

Abstract Extracellular vesicles (EVs) such as exosomes are nano-sized vesicles that carry proteins and miRNAs and can transmit signals between cells. We hypothesized that exosomes from endothelial cells can transmit protective signals to cardiomyocytes. Co-culture of primary adult rat cardiomyocytes...

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Bibliographic Details
Main Authors: Sean M. Davidson, Jaime A. Riquelme, Ying Zheng, Jose M. Vicencio, Sergio Lavandero, Derek M. Yellon
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-018-34357-z