Statins Activate Human PPAR𝛼 Promoter and Increase PPAR𝛼 mRNA Expression and Activation in HepG2 Cells
Statins increase peroxisome proliferator-activated receptor 𝛼 (PPAR𝛼) mRNA expression, but the mechanism of this increased PPAR𝛼 production remains elusive. To examine the regulation of PPAR𝛼 production, we examined the effect of 7 statins (atorvastatin, cerivastatin, fluvastatin, pitavastatin, prav...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2008-01-01
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| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2008/316306 |