A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity

A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity

Across many studies, animals with enhanced synaptic plasticity exhibit either enhanced or impaired learning, raising a conceptual puzzle: how enhanced plasticity can yield opposite learning outcomes? Here, we show that the recent history of experience can determine whether mice with enhanced plastic...

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Bibliographic Details
Main Authors: TD Barbara Nguyen-Vu, Grace Q Zhao, Subhaneil Lahiri, Rhea R Kimpo, Hanmi Lee, Surya Ganguli, Carla J Shatz, Jennifer L Raymond
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-02-01
Series:eLife
Subjects:
learning & memory
cerebellum
synaptic plasticity
Online Access:https://elifesciences.org/articles/20147

Internet

https://elifesciences.org/articles/20147

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