Real-Time, Label-Free Detection of Biomolecular Interactions in Sandwich Assays by the Oblique-Incidence Reflectivity Difference Technique

One of the most important goals in proteomics is to detect the real-time kinetics of diverse biomolecular interactions. Fluorescence, which requires extrinsic tags, is a commonly and widely used method because of its high convenience and sensitivity. However, in order to maintain the conformational...

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Bibliographic Details
Main Authors: Yung-Shin Sun, Xiangdong Zhu
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/14/12/23307