Iron from haemoglobin and haemin modulates nucleotide hydrolysis in Trichomonas vaginalis

Iron from haemoglobin and haemin modulates nucleotide hydrolysis in Trichomonas vaginalis

Extracellular ATP may act as a danger signalling molecule, inducing inflammation and immune responses in infection sites. The ectonucleotidases NTPDase and ecto-5’-nucleotidase are enzymes that modulate extracellular nucleotide levels; these enzymes have been previously characterised in Trichomonas...

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Bibliographic Details
Main Authors: Patrícia de Brum Vieira, Nícolas Luiz Feijó Silva, Luiza Wilges Kist, Giovanna Medeiros Tavares de Oliveira, Maurício Reis Bogo, Geraldo Atillio De Carli, Alexandre José Macedo, Tiana Tasca
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2015-04-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Trichomonas vaginalis
iron
nucleoside triphosphate diphosphohydrolase
ecto-5’-nucleotidase
nucleotide hydrolysis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000200201&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000200201&lng=en&tlng=en

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