Oligonucleotide analogues with cationic backbone linkages

Their unique ability to selectively bind specific nucleic acid sequences makes oligonucleotides promising bioactive agents. However, modifications of the nucleic acid structure are an essential prerequisite for their application in vivo or even in cellulo. The oligoanionic backbone structure of olig...

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Bibliographic Details
Main Authors: Melissa Meng, Christian Ducho
Format: Article
Language:English
Published: Beilstein-Institut 2018-06-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
DNA
Online Access:https://doi.org/10.3762/bjoc.14.111