Herb-Drug Interaction between the Traditional Hepatoprotective Formulation and Sorafenib on Hepatotoxicity, Histopathology and Pharmacokinetics in Rats

Sorafenib has been used as a standard therapy for advanced hepatocellular carcinoma (HCC). In Asia, patients with HCC are potentially treated with the combination of sorafenib and Chinese herbal medicines to improve the efficiency and reduce the side effects of sorafenib. However, limited informatio...

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Bibliographic Details
Main Authors: Chin-Tsung Ting, Yung-Yi Cheng, Tung-Hu Tsai
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/7/1034