GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness

GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness

Growth differentiation factor 15 (GDF15) is a stress molecule produced in response to mitochondrial, metabolic and inflammatory stress with a number of beneficial effects on metabolism. However, at the level of skeletal muscle it is still unclear whether GDF15 is beneficial or detrimental. The aim o...

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Bibliographic Details
Main Authors: Maria Conte, Morena Martucci, Giovanni Mosconi, Antonio Chiariello, Maria Cappuccilli, Valentina Totti, Aurelia Santoro, Claudio Franceschi, Stefano Salvioli
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
GDF15
physical activity
sedentarity
inflammation
skeletal muscle
healthy aging
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00915/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00915/full

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