Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation

<p>Abstract</p> <p>Background</p> <p>The ability to expand virus- or tumor-specific T cells without damaging their functional capabilities is critical for success adoptive transfer immunotherapy of patients with opportunistic infection or tumor. Careful comparisons can...

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Bibliographic Details
Main Authors: Kurlander Roger J, Li Yixin
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/104