Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation
<p>Abstract</p> <p>Background</p> <p>The ability to expand virus- or tumor-specific T cells without damaging their functional capabilities is critical for success adoptive transfer immunotherapy of patients with opportunistic infection or tumor. Careful comparisons can...
Main Authors: | Kurlander Roger J, Li Yixin |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-10-01
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Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/8/1/104 |
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