Biological and clinical features of triple negative Invasive Lobular Carcinomas of the breast. Clinical outcome and actionable molecular alterations

Biological and clinical features of triple negative Invasive Lobular Carcinomas of the breast. Clinical outcome and actionable molecular alterations

Background: We report here for the first time, a comprehensive characterization of biological and clinical features of early-stage triple negative Invasive Lobular Carcinomas(TN-ILCs) Methods: We analyzed all consecutive patients with early-stage TN-ILC operated at two reference cancer-centers betwe...

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Bibliographic Details
Main Authors: Fabio Conforti, Laura Pala, Eleonora Pagan, Elena Guerini Rocco, Vincenzo Bagnardi, Emilia Montagna, Giulia Peruzzotti, Tommaso De Pas, Caterina Fumagalli, Silvana Pileggi, Chiara Pesenti, Sergio Marchini, Giovanni Corso, Caterina Marchio’, Anna Sapino, Rossella Graffeo, Laetitia Collet, Philippe Aftimos, Christos Sotiriou, Martine Piccart, Richard D. Gelber, Giuseppe Viale, Marco Colleoni, Aron Goldhirsch
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Breast
Subjects:
Triple negative invasive lobular carcinoma
ERBB2 gene mutations
HER2/PI3K/AKT pathway
Androgen receptor
Luminal androgen receptor subtype
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977621004070

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http://www.sciencedirect.com/science/article/pii/S0960977621004070

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