Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes.

Acetylcholine receptors are pentameric ligand-gated channels involved in excitatory neuro-transmission in both vertebrates and invertebrates. In nematodes, they represent major targets for cholinergic agonist or antagonist anthelmintic drugs. Despite the large diversity of acetylcholine-receptor sub...

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Bibliographic Details
Main Authors: Elise Courtot, Claude L Charvet, Robin N Beech, Abdallah Harmache, Adrian J Wolstenholme, Lindy Holden-Dye, Vincent O'Connor, Nicolas Peineau, Debra J Woods, Cedric Neveu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4666645?pdf=render