Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae

Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae

Abstract Background In fast-growing bacteria, the genomic location of ribosomal protein (RP) genes is biased towards the replication origin (oriC). This trait allows optimizing their expression during exponential phase since oriC neighboring regions are in higher dose due to multifork replication. R...

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Main Authors: Alfonso Soler-Bistué, Sebastián Aguilar-Pierlé, Marc Garcia-Garcerá, Marie-Eve Val, Odile Sismeiro, Hugo Varet, Rodrigo Sieira, Evelyne Krin, Ole Skovgaard, Diego J. Comerci, Eduardo P. C. Rocha, Didier Mazel
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Biology
Subjects:
Ribosomal proteins
Macromolecular crowding
Growth rate
Vibrio cholerae
Bacterial chromosome
Bacterial physiology
Online Access:http://link.springer.com/article/10.1186/s12915-020-00777-5

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http://link.springer.com/article/10.1186/s12915-020-00777-5

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