A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits.

A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits.

We investigated in a rabbit model, the eye distribution of topically instilled benzalkonium_(BAK) chloride a commonly used preservative in eye drops using mass spectrometry imaging. Three groups of three New Zealand rabbits each were used: a control one without instillation, one receiving 0.01%BAK t...

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Bibliographic Details
Main Authors: Françoise Brignole-Baudouin, Nicolas Desbenoit, Gregory Hamm, Hong Liang, Jean-Pierre Both, Alain Brunelle, Isabelle Fournier, Vincent Guerineau, Raphael Legouffe, Jonathan Stauber, David Touboul, Maxence Wisztorski, Michel Salzet, Olivier Laprevote, Christophe Baudouin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209668/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209668/pdf/?tool=EBI

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