Analysis of Antimicrobial-Triggered Membrane Depolarisation Using Voltage Sensitive Dyes

The bacterial cytoplasmic membrane is a major inhibitory target for antimicrobial compounds. Commonly, although not exclusively, these compounds unfold their antimicrobial activity by disrupting the essential barrier function of the cell membrane. As a consequence, membrane permeability assays are c...

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Bibliographic Details
Main Authors: J. Derk te Winkel, Declan A. Gray, Kenneth H. Seistrup, Leendert W. Hamoen, Henrik eStrahl
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00029/full