Androgen receptor drives cellular senescence.

The accepted androgen receptor (AR) role is to promote proliferation and survival of prostate epithelium and thus prostate cancer progression. While growth-inhibitory, tumor-suppressive AR effects have also been documented, the underlying mechanisms are poorly understood. Here, we for the first time...

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Bibliographic Details
Main Authors: Yelena Mirochnik, Dorina Veliceasa, Latanya Williams, Kelly Maxwell, Alexander Yemelyanov, Irina Budunova, Olga V Volpert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3293868?pdf=render