Mesenchymal Stem Cell Derived Biocompatible Membrane Vesicles Demonstrate Immunomodulatory Activity Inhibiting Activation and proliferation of Human Mononuclear Cells

Mesenchymal Stem Cell Derived Biocompatible Membrane Vesicles Demonstrate Immunomodulatory Activity Inhibiting Activation and proliferation of Human Mononuclear Cells

Immune-mediated diseases are characterized by abnormal activity of the immune system. The cytochalasin B-induced membrane vesicles (CIMVs) are innovative therapeutic instruments. However, the immunomodulating activity of human mesenchymal stem cell (MSC)-derived CIMVs (CIMVs-MSCs) remains unknown. T...

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Bibliographic Details
Main Authors: Marina O. Gomzikova, Sevindzh K. Kletukhina, Sirina V. Kurbangaleeva, Olga A. Neustroeva, Olga S. Vasileva, Ekaterina E. Garanina, Svetlana F. Khaiboullina, Albert A. Rizvanov
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceutics
Subjects:
extracellular vesicles
microvesicles
cytochalasin B-induced membrane vesicles
mesenchymal stem cells
immunosuppression
immunomodulation
Online Access:https://www.mdpi.com/1999-4923/12/6/577

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https://www.mdpi.com/1999-4923/12/6/577

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