Enhancement of the Oral Bioavailability of Fexofenadine Hydrochloride via Cremophor® El-Based Liquisolid Tablets

Enhancement of the Oral Bioavailability of Fexofenadine Hydrochloride via Cremophor® El-Based Liquisolid Tablets

Purpose: The current work aimed to develop promising Fexofenadine hydrochloride (FXD) liquisolid tablets able to increase its oral bioavailability and shorten time to reach maximum plasma concentrations (Tmax). Methods: Eighteen liquisolid powders were developed based on 3 variables; (i) vehicle typ...

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Bibliographic Details
Main Authors: Soad Ali Yehia, Mohamed Shafik El-Ridi, Mina Ibrahim Tadros, Nolwa Gamal El-Sherif
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-11-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Fexofenadine hydrochloride
Liquisolid tablets
Cremophor® EL
Pharmacokinetics
Oral bioavailability
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-5-569.pdf

Internet

http://journals.tbzmed.ac.ir/APB/Manuscript/APB-5-569.pdf

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