Suppressive effect of glycyrrhizic acid against lipopolysaccharide-induced neuroinflammation and cognitive impairment in C57 mice via toll-like receptor 4 signaling pathway

Suppressive effect of glycyrrhizic acid against lipopolysaccharide-induced neuroinflammation and cognitive impairment in C57 mice via toll-like receptor 4 signaling pathway

Background: Glycyrrhizinic acid (GA), a major active ingredient enriched in the roots of licorice, possesses well-confirmed anti-inflammatory effects. Objective: To evaluate the underlying mechanisms of GA against lipopolysaccharide (LPS)-induced chronic neuroinflammation and memory impairment. Desi...

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Bibliographic Details
Main Authors: Wenfeng Liu, Shun Huang, Yonglian Li, Kun Zhang, Xi Zheng
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2019-04-01
Series:Food & Nutrition Research
Subjects:
glycyrrhizinic acid
LPS
neuroinflammation
toll-like receptor (TLR4)
Alzheimer’s disease
Online Access:https://foodandnutritionresearch.net/index.php/fnr/article/view/1516/9225

Internet

https://foodandnutritionresearch.net/index.php/fnr/article/view/1516/9225

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