The biological effect of large single doses: a possible role for non-targeted effects in cell inactivation.

BACKGROUND AND PURPOSE:Novel radiotherapy techniques increasingly use very large dose fractions. It has been argued that the biological effect of large dose fractions may differ from that of conventional fraction sizes. The purpose was to study the biological effect of large single doses. MATERIAL A...

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Bibliographic Details
Main Authors: Marlon R Veldwijk, Bo Zhang, Frederik Wenz, Carsten Herskind
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3898915?pdf=render